Rational Modification of the Biological Profile of GPCR Ligands through Combination with Other Biologically Active Moieties
Author:
Affiliation:
1. Pharmazeutische und Medizinische Chemie; Institut für Pharmazie und Lebensmittelchemie; Julius-Maximilians-Universität Würzburg; Würzburg Germany
Funder
Deutsche Forschungsgemeinschaft
Publisher
Wiley
Subject
Drug Discovery,Pharmaceutical Science
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1002/ardp.201500079/fullpdf
Reference99 articles.
1. Beta-Blockers in Hypertension and Angina Pectoris
2. Crystal structure of the β2 adrenergic receptor–Gs protein complex
3. High-Resolution Crystal Structure of an Engineered Human β 2 -Adrenergic G Protein–Coupled Receptor
4. Crystal structure of the µ-opioid receptor bound to a morphinan antagonist
5. Regulation of GPCR activity, trafficking and localization by GPCR-interacting proteins
Cited by 7 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Designing drugs and chemical probes with the dualsteric approach;Chemical Society Reviews;2023
2. Modulation of opioid receptor affinity and efficacy via N-substitution of 9β-hydroxy-5-(3-hydroxyphenyl)morphan: Synthesis and computer simulation study;Bioorganic & Medicinal Chemistry;2017-04
3. Bitopic Ligands and Metastable Binding Sites: Opportunities for G Protein-Coupled Receptor (GPCR) Medicinal Chemistry;Journal of Medicinal Chemistry;2017-02-15
4. The dual-acting AChE inhibitor and H3 receptor antagonist UW-MD-72 reverses amnesia induced by scopolamine or dizocilpine in passive avoidance paradigm in rats;Physiology & Behavior;2016-10
5. Multiple Targeting Approaches on Histamine H3 Receptor Antagonists;Frontiers in Neuroscience;2016-05-30
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3