Structural Basis of Microtubule Stabilization by Discodermolide

Author:

Prota Andrea E.1ORCID,Bargsten Katja12,Redondo-Horcajo Mariano3ORCID,Smith Amos B.4,Yang Chia-Ping H.5,McDaid Hayley M.5,Paterson Ian6,Horwitz Susan B.5,Fernando Díaz José3ORCID,Steinmetz Michel O.1

Affiliation:

1. Laboratory of Biomolecular Research; Department of Biology and Chemistry; Paul Scherrer Institut; OFLC/111 5232 Villigen PSI Switzerland

2. Current address: Department of Biochemistry; University of Zürich; Winterthurerstrasse 190 8057 Zürich Switzerland

3. Chemical and Physical Biology; Centro de Investigaciones Biológicas; Consejo Superior de Investigaciones Científicas CIB-CSIC; Ramiro de Maeztu 9 28040 Madrid Spain

4. Department of Chemistry; University of Pennsylvania; 231 S. 34th Street Philadelphia PA 19104 USA

5. Department of Molecular Pharmacology; Albert Einstein College of Medicine; 1300 Morris Park Avenue Golding 201 Bronx NY 1046 USA

6. University Chemical Laboratory; Cambridge University; Lensfield Road Cambridge CB2 1EW UK

Funder

Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung

Ministerio de Economía y Competitividad

National Cancer Institute

Breast Cancer Research Foundation

National Foundation for Cancer Research

Publisher

Wiley

Subject

Organic Chemistry,Molecular Biology,Molecular Medicine,Biochemistry

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