Epigenomic features related to microglia are associated with attenuated effect of APOE ε4 on Alzheimer's disease risk in humans-Reference-Cited by-同舟云学术

Epigenomic features related to microglia are associated with attenuated effect of APOE ε4 on Alzheimer's disease risk in humans

Published:2021-09-05 Issue: Volume: Page:
ISSN:1552-5260
Container-title:Alzheimer's & Dementia
language:en
Short-container-title:Alzheimer's & Dementia

Author:

Ma Yiyi¹,Yu Lei²³,Olah Marta¹,Smith Rebecca⁴,Oatman Stephanie R.⁵,Allen Mariet⁵,Pishva Ehsan⁴,Zhang Bin⁶⁷,Menon Vilas¹,Ertekin‐Taner Nilüfer⁵⁸,Lunnon Katie⁴,Bennett David A.²³,Klein Hans‐Ulrich¹,De Jager Philip L.¹⁹

Affiliation:

1. Center for Translational & Computational Neuroimmunology Department of Neurology Columbia University Medical Center New York New York USA

2. Rush Alzheimer's Disease Center Rush University Medical Center Chicago Illinois USA

3. Department of Neurological Sciences Rush University Medical Center Chicago Illinois USA

4. College of Medicine and Health University of Exeter Medical School, Exeter University Exeter UK

5. Department of Neuroscience Mayo Clinic Florida Jacksonville Florida USA

6. Department of Genetics and Genomic Sciences Icahn School of Medicine at Mount Sinai New York New York USA

7. Icahn Institute of Genomics and Multiscale Biology Icahn School of Medicine at Mount Sinai New York New York USA

8. Department of Neurology Mayo Clinic Florida Jacksonville Florida USA

9. Cell Circuits Program Broad Institute Cambridge Massachusetts USA

Funder

National Institute of Neurological Disorders and Stroke

National Institute on Aging

Arizona Department of Health Services

Arizona Biomedical Research Commission

Publisher

Wiley

Subject

Psychiatry and Mental health,Cellular and Molecular Neuroscience,Geriatrics and Gerontology,Neurology (clinical),Developmental Neuroscience,Health Policy,Epidemiology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/alz.12425

Reference31 articles.

1. Effects of Age, Sex, and Ethnicity on the Association Between Apolipoprotein E Genotype and Alzheimer Disease

2. Power and Pitfalls of the Genome-Wide Association Study Approach to Identify Genes for Alzheimer’s Disease

3. Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease

4. Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

5. APOE genotype predicts when — not whether — one is predisposed to develop Alzheimer disease

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