Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing
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Published:2019-02-28
Issue:3
Volume:51
Page:414-430
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ISSN:1061-4036
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Container-title:Nature Genetics
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language:en
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Short-container-title:Nat Genet
Author:
Kunkle Brian W.ORCID, , Grenier-Boley Benjamin, Sims Rebecca, Bis Joshua C., Damotte Vincent, Naj Adam C., Boland Anne, Vronskaya Maria, van der Lee Sven J.ORCID, Amlie-Wolf AlexandreORCID, Bellenguez CélineORCID, Frizatti Aura, Chouraki Vincent, Martin Eden R., Sleegers KristelORCID, Badarinarayan Nandini, Jakobsdottir Johanna, Hamilton-Nelson Kara L., Moreno-Grau Sonia, Olaso Robert, Raybould Rachel, Chen YuningORCID, Kuzma Amanda B., Hiltunen Mikko, Morgan Taniesha, Ahmad Shahzad, Vardarajan Badri N., Epelbaum Jacques, Hoffmann Per, Boada Merce, Beecham Gary W., Garnier Jean-Guillaume, Harold Denise, Fitzpatrick Annette L., Valladares Otto, Moutet Marie-Laure, Gerrish Amy, Smith Albert V., Qu Liming, Bacq Delphine, Denning Nicola, Jian Xueqiu, Zhao Yi, Del Zompo Maria, Fox Nick C., Choi Seung-Hoan, Mateo Ignacio, Hughes Joseph T., Adams Hieab H.ORCID, Malamon John, Sanchez-Garcia Florentino, Patel Yogen, Brody Jennifer A.ORCID, Dombroski Beth A., Naranjo Maria Candida Deniz, Daniilidou Makrina, Eiriksdottir Gudny, Mukherjee Shubhabrata, Wallon David, Uphill James, Aspelund ThorORCID, Cantwell Laura B., Garzia Fabienne, Galimberti Daniela, Hofer Edith, Butkiewicz Mariusz, Fin Bertrand, Scarpini Elio, Sarnowski Chloe, Bush Will S.ORCID, Meslage Stéphane, Kornhuber Johannes, White Charles C., Song Yuenjoo, Barber Robert C.ORCID, Engelborghs Sebastiaan, Sordon Sabrina, Voijnovic Dina, Adams Perrie M., Vandenberghe Rik, Mayhaus Manuel, Cupples L. AdrienneORCID, Albert Marilyn S., De Deyn Peter P.ORCID, Gu Wei, Himali Jayanadra J.ORCID, Beekly Duane, Squassina AlessioORCID, Hartmann Annette M., Orellana Adelina, Blacker Deborah, Rodriguez-Rodriguez Eloy, Lovestone Simon, Garcia Melissa E., Doody Rachelle S., Munoz-Fernadez Carmen, Sussams Rebecca, Lin HonghuangORCID, Fairchild Thomas J., Benito Yolanda A., Holmes Clive, Karamujić-Čomić Hata, Frosch Matthew P., Thonberg Hakan, Maier Wolfgang, Roshchupkin GennadyORCID, Ghetti BernardinoORCID, Giedraitis VilmantasORCID, Kawalia Amit, Li ShuoORCID, Huebinger Ryan M., Kilander Lena, Moebus Susanne, Hernández Isabel, Kamboh M. Ilyas, Brundin RoseMarie, Turton James, Yang QiongORCID, Katz Mindy J., Concari Letizia, Lord Jenny, Beiser Alexa S., Keene C. Dirk, Helisalmi Seppo, Kloszewska Iwona, Kukull Walter A., Koivisto Anne Maria, Lynch Aoibhinn, Tarraga Lluís, Larson Eric B., Haapasalo Annakaisa, Lawlor Brian, Mosley Thomas H., Lipton Richard B., Solfrizzi Vincenzo, Gill MichaelORCID, Longstreth W. T., Montine Thomas J., Frisardi Vincenza, Diez-Fairen Monica, Rivadeneira FernandoORCID, Petersen Ronald C., Deramecourt Vincent, Alvarez Ignacio, Salani Francesca, Ciaramella Antonio, Boerwinkle Eric, Reiman Eric M., Fievet Nathalie, Rotter Jerome I., Reisch Joan S., Hanon Olivier, Cupidi Chiara, Andre Uitterlinden A. G., Royall Donald R., Dufouil Carole, Maletta Raffaele Giovanni, de Rojas Itziar, Sano Mary, Brice Alexis, Cecchetti Roberta, George-Hyslop Peter St, Ritchie Karen, Tsolaki MagdaORCID, Tsuang Debby W., Dubois Bruno, Craig David, Wu Chuang-Kuo, Soininen Hilkka, Avramidou Despoina, Albin Roger L., Fratiglioni Laura, Germanou Antonia, Apostolova Liana G., Keller Lina, Koutroumani Maria, Arnold Steven E., Panza Francesco, Gkatzima Olymbia, Asthana Sanjay, Hannequin Didier, Whitehead Patrice, Atwood Craig S.ORCID, Caffarra Paolo, Hampel Harald, Quintela Inés, Carracedo Ángel, Lannfelt Lars, Rubinsztein David C.ORCID, Barnes Lisa L., Pasquier FlorenceORCID, Frölich Lutz, Barral Sandra, McGuinness Bernadette, Beach Thomas G., Johnston Janet A., Becker James T.ORCID, Passmore Peter, Bigio Eileen H., Schott Jonathan M.ORCID, Bird Thomas D., Warren Jason D., Boeve Bradley F., Lupton Michelle K.ORCID, Bowen James D.ORCID, Proitsi Petra, Boxer Adam, Powell John F., Burke James R.ORCID, Kauwe John S. K., Burns Jeffrey M., Mancuso MichelangeloORCID, Buxbaum Joseph D., Bonuccelli Ubaldo, Cairns Nigel J., McQuillin AndrewORCID, Cao Chuanhai, Livingston Gill, Carlson Chris S., Bass Nicholas J., Carlsson Cynthia M., Hardy John, Carney Regina M., Bras Jose, Carrasquillo Minerva M., Guerreiro Rita, Allen Mariet, Chui Helena C., Fisher ElizabethORCID, Masullo Carlo, Crocco Elizabeth A., DeCarli Charles, Bisceglio Gina, Dick Malcolm, Ma Li, Duara Ranjan, Graff-Radford Neill R., Evans Denis A., Hodges Angela, Faber Kelley M., Scherer Martin, Fallon Kenneth B., Riemenschneider Matthias, Fardo David W.ORCID, Heun Reinhard, Farlow Martin R., Kölsch Heike, Ferris Steven, Leber Markus, Foroud Tatiana M., Heuser Isabella, Galasko Douglas R., Giegling Ina, Gearing Marla, Hüll Michael, Geschwind Daniel H., Gilbert John R., Morris John, Green Robert C., Mayo Kevin, Growdon John H., Feulner Thomas, Hamilton Ronald L.ORCID, Harrell Lindy E., Drichel Dmitriy, Honig Lawrence S., Cushion Thomas D., Huentelman Matthew J., Hollingworth Paul, Hulette Christine M., Hyman Bradley T., Marshall Rachel, Jarvik Gail P., Meggy Alun, Abner Erin, Menzies Georgina E.ORCID, Jin Lee-Way, Leonenko Ganna, Real Luis M., Jun Gyungah R., Baldwin Clinton T., Grozeva Detelina, Karydas Anna, Russo Giancarlo, Kaye Jeffrey A., Kim Ronald, Jessen Frank, Kowall Neil W., Vellas Bruno, Kramer Joel H., Vardy Emma, LaFerla Frank M., Jöckel Karl-Heinz, Lah James J., Dichgans Martin, Leverenz James B., Mann David, Levey Allan I., Pickering-Brown StuartORCID, Lieberman Andrew P., Klopp Norman, Lunetta Kathryn L.ORCID, Wichmann H-Erich, Lyketsos Constantine G., Morgan KevinORCID, Marson Daniel C., Brown Kristelle, Martiniuk Frank, Medway Christopher, Mash Deborah C., Nöthen Markus M., Masliah Eliezer, Hooper Nigel M.ORCID, McCormick Wayne C., Daniele Antonio, McCurry Susan M., Bayer Anthony, McDavid Andrew N.ORCID, Gallacher JohnORCID, McKee Ann C., van den Bussche Hendrik, Mesulam Marsel, Brayne Carol, Miller Bruce L., Riedel-Heller Steffi, Miller Carol A., Miller Joshua W., Al-Chalabi AmmarORCID, Morris John C., Shaw Christopher E., Myers Amanda J., Wiltfang Jens, O’Bryant Sid, Olichney John M., Alvarez Victoria, Parisi Joseph E., Singleton Andrew B., Paulson Henry L., Collinge John, Perry William R., Mead Simon, Peskind Elaine, Cribbs David H., Rossor Martin, Pierce Aimee, Ryan Natalie S., Poon Wayne W.ORCID, Nacmias Benedetta, Potter Huntington, Sorbi Sandro, Quinn Joseph F., Sacchinelli EleonoraORCID, Raj Ashok, Spalletta Gianfranco, Raskind Murray, Caltagirone Carlo, Bossù Paola, Orfei Maria Donata, Reisberg Barry, Clarke RobertORCID, Reitz Christiane, Smith A David, Ringman John M., Warden Donald, Roberson Erik D.ORCID, Wilcock Gordon, Rogaeva Ekaterina, Bruni Amalia Cecilia, Rosen Howard J., Gallo Maura, Rosenberg Roger N., Ben-Shlomo Yoav, Sager Mark A., Mecocci Patrizia, Saykin Andrew J.ORCID, Pastor PauORCID, Cuccaro Michael L., Vance Jeffery M., Schneider Julie A., Schneider Lori S., Slifer Susan, Seeley William W., Smith Amanda G., Sonnen Joshua A., Spina Salvatore, Stern Robert A., Swerdlow Russell H., Tang Mitchell, Tanzi Rudolph E.ORCID, Trojanowski John Q., Troncoso Juan C., Van Deerlin Vivianna M., Van Eldik Linda J., Vinters Harry V., Vonsattel Jean Paul, Weintraub Sandra, Welsh-Bohmer Kathleen A., Wilhelmsen Kirk C., Williamson Jennifer, Wingo Thomas S.ORCID, Woltjer Randall L., Wright Clinton B., Yu Chang-En, Yu Lei, Saba Yasaman, Pilotto Alberto, Bullido Maria J.ORCID, Peters Oliver, Crane Paul K., Bennett David, Bosco Paola, Coto Eliecer, Boccardi Virginia, De Jager Phil L.ORCID, Lleo Alberto, Warner Nick, Lopez Oscar L., Ingelsson Martin, Deloukas PanagiotisORCID, Cruchaga CarlosORCID, Graff Caroline, Gwilliam Rhian, Fornage Myriam, Goate Alison M.ORCID, Sanchez-Juan Pascual, Kehoe Patrick G., Amin Najaf, Ertekin-Taner Nilifur, Berr ClaudineORCID, Debette Stéphanie, Love Seth, Launer Lenore J., Younkin Steven G., Dartigues Jean-Francois, Corcoran Chris, Ikram M. ArfanORCID, Dickson Dennis W.ORCID, Nicolas Gael, Campion Dominique, Tschanz JoAnn, Schmidt Helena, Hakonarson Hakon, Clarimon Jordi, Munger Ron, Schmidt Reinhold, Farrer Lindsay A., Van Broeckhoven ChristineORCID, C. O’Donovan MichaelORCID, DeStefano Anita L., Jones LesleyORCID, Haines Jonathan L., Deleuze Jean-Francois, Owen Michael J.ORCID, Gudnason Vilmundur, Mayeux Richard, Escott-Price ValentinaORCID, Psaty Bruce M., Ramirez AlfredoORCID, Wang Li-San, Ruiz Agustin, van Duijn Cornelia M., Holmans Peter A., Seshadri Sudha, Williams Julie, Amouyel PhillippeORCID, Schellenberg Gerard D., Lambert Jean-CharlesORCID, Pericak-Vance Margaret A.ORCID, , ,
Publisher
Springer Science and Business Media LLC
Reference185 articles.
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