Cascade Reductive Rearrangement for the Stereoselective Synthesis of Multifunctional Piperidinones: A Combined Experimental and Computational Study-Reference-Cited by-同舟云学术

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Cascade Reductive Rearrangement for the Stereoselective Synthesis of Multifunctional Piperidinones: A Combined Experimental and Computational Study

Published:2020-02-19 Issue:7 Volume:5 Page:2332-2336
ISSN:2365-6549
Container-title:ChemistrySelect
language:en
Short-container-title:ChemistrySelect

Author:

Zhu Guoxun¹,Ma Lei²,Zhang Kaixin¹,Zhou Zhi²,Song Huacan¹,Yi Wei¹²^ORCID

Affiliation:

1. School of Chemical Engineering and TechnologySun Yat-sen University 135 Xin Gang West Road Guangzhou 510275 P.R. China

2. Key Laboratory of Molecular Target and Clinical Pharmacology & the State Key Laboratory of Respiratory DiseaseSchool of Pharmaceutical Sciences & the Fifth Affiliated Hospital, Guangzhou Medical University Guangzhou, Guangdong 511436 P. R. China

Funder

National Natural Science Foundation of China

Publisher

Wiley

Subject

General Chemistry

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/slct.201904106

Reference60 articles.

2. 6-Membered Pyrrololactams: An Overview of Current Synthetic Approaches to their Preparation

3. The development of piperidinones as potent MDM2-P53 protein-protein interaction inhibitors for cancer therapy

4. Medicinal Chemistry Strategies to Disrupt the p53-MDM2/MDMX Interaction

5. p53-Mdm2 Interaction Inhibitors as Novel Nongenotoxic Anticancer Agents

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