Facing the gem-Dialkyl Effect in Enzyme Inhibitor Design: Preparation of Homocycloleucine-Based Azadipeptide Nitriles
Author:
Publisher
Wiley
Subject
General Chemistry,Catalysis,Organic Chemistry
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1002/chem.201101350/fullpdf
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1. Human and Parasitic Papain-Like Cysteine Proteases: Their Role in Physiology and Pathology and Recent Developments in Inhibitor Design
2. Development of Nitrile-Based Peptidic Inhibitors of Cysteine Cathepsins
3. Peptidomimetic Inhibitors of Cathepsin K
4. New Cathepsin Inhibitors to Explore the Fluorophilic Properties of the S 2 Pocket of Cathepsin B: Design, Synthesis, and Biological Evaluation
5. Azadipeptidnitrile – hochpotente und proteolysestabile Inhibitoren Papain-ähnlicher Cysteinproteasen
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