Limiting the Number of Potential Binding Modes by Introducing Symmetry into Ligands: Structure-Based Design of Inhibitors for Trypsin-Like Serine Proteases-Reference-Cited by-同舟云学术

Limiting the Number of Potential Binding Modes by Introducing Symmetry into Ligands: Structure-Based Design of Inhibitors for Trypsin-Like Serine Proteases

Published:2015-12-02 Issue:2 Volume:22 Page:610-625
ISSN:0947-6539
Container-title:Chemistry - A European Journal
language:en
Short-container-title:Chem. Eur. J.

Author:

Furtmann Norbert,Häußler Daniela,Scheidt Tamara,Stirnberg Marit,Steinmetzer Torsten,Bajorath Jürgen,Gütschow Michael

Funder

Jürgen Manchot Foundation, Düsseldorf, Germany

Bonn International Graduate School of Drug Sciences (BIGS DrugS)

German Research Foundation

STI 660/1-1

Maria von Linden-Program of the University of Bonn

Publisher

Wiley

Subject

General Chemistry,Catalysis,Organic Chemistry

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/chem.201503534/fullpdf

Reference55 articles.

1. Docking and scoring in virtual screening for drug discovery: methods and applications

2. Computational Methods in Drug Discovery

3. Quo Vadis, Virtual Screening? A Comprehensive Survey of Prospective Applications

4. Beware of docking!

5. http://www.rcsb.org

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