Straightforward synthesis of biologically valuable nonsymmetrical malonamides under mild conditions-Reference-Cited by-同舟云学术

Straightforward synthesis of biologically valuable nonsymmetrical malonamides under mild conditions

Published:2022 Issue:7 Volume:24 Page:3035-3041
ISSN:1463-9262
Container-title:Green Chemistry
language:en
Short-container-title:Green Chem.

Author:

Zhang Zhiguo¹^ORCID,Cao Xiyang¹,Wang Gang¹,Zhang Guisheng¹^ORCID,Zhang Xingjie¹^ORCID

Affiliation:

1. Key Laboratory of Green Chemical Media and Reactions, Ministry of Education; Collaborative Innovation Centre of Henan Province for Green Manufacturing of Fine Chemicals; NMPA Key Laboratory for Research and Evaluation of Innovative Drug; School of Chemistry and Chemical Engineering, Henan Normal University, 46 East of Construction Road, Xinxiang, Henan 453007, China

Abstract

A flexible method is developed for the synthesis of nonsymmetrical malonamides from isocyanates and β-ketoamides. The high efficiency and practicability enabled rapid entry to diverse precursors of malonamides pharmaceuticals.

Funder

National Natural Science Foundation of China

Higher Education Discipline Innovation Project

China Postdoctoral Science Foundation

Natural Science Foundation of Henan Province

Publisher

Royal Society of Chemistry (RSC)

Subject

Pollution,Environmental Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/GC/D2GC00395C

Reference102 articles.