Generation of Polar Semi-Saturated Bicyclic Pyrazoles for Fragment-Based Drug-Discovery Campaigns.-Reference-Cited by-同舟云学术

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Generation of Polar Semi-Saturated Bicyclic Pyrazoles for Fragment-Based Drug-Discovery Campaigns.

Published:2018-06-19 Issue:41 Volume:24 Page:10443-10451
ISSN:0947-6539
Container-title:Chemistry - A European Journal
language:en
Short-container-title:Chem. Eur. J.

Author:

Luise Nicola¹^ORCID,Wyatt Paul G.¹

Affiliation:

1. Drug Discovery Unit; School of Life Sciences; University of Dundee; Dow Street Dundee DD1 5EH Scotland UK

Funder

Nicholl-Lindsay Studentship

Publisher

Wiley

Subject

General Chemistry,Catalysis,Organic Chemistry

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/chem.201801313/fullpdf

Reference83 articles.

1. Design Principles for Fragment Libraries: Maximizing the Value of Learnings from Pharma Fragment-Based Drug Discovery (FBDD) Programs for Use in Academia

2. Twenty years on: the impact of fragments on drug discovery

3. Fragment-based lead discovery grows up

4. Fragment-Based Lead Discovery and Design

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1. Couple-close construction of polycyclic rings from diradicals;Nature;2024-03-13

2. Synthesis of ring fused difluoromethyl pyrazolines and pyrazoles by cycloaddition of difluoroacetohydrazonoyl bromides with cyclic α,β-Unsaturated carbonyl compounds;Tetrahedron;2023-12

3. Modular, automated synthesis of spirocyclic tetrahydronaphthyridines from primary alkylamines;Communications Chemistry;2023-10-04

4. Straightforward access to heterofused ε-sultams annelated on face [d];Tetrahedron Letters;2023-06

5. A close look into the biological and synthetic aspects of fused pyrazole derivatives;European Journal of Medicinal Chemistry;2022-12

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