Consistency of the Novel Equations for Determination of Hepatic Clearance and Drug Time Course in Liver that Account for the Difference in Drug Ionization in Extracellular and Intracellular Tissue Water-Reference-Cited by-同舟云学术

Consistency of the Novel Equations for Determination of Hepatic Clearance and Drug Time Course in Liver that Account for the Difference in Drug Ionization in Extracellular and Intracellular Tissue Water

Published:2012-02 Issue:2 Volume:101 Page:516-518
ISSN:0022-3549
Container-title:Journal of Pharmaceutical Sciences
language:en
Short-container-title:Journal of Pharmaceutical Sciences

Author:

Berezhkovskiy Leonid M.,Liu Ning,Halladay Jason S.

Publisher

Elsevier BV

Subject

Pharmaceutical Science

Reference5 articles.

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3. Prediction of human clearance of twenty-nine drugs from hepatic microsomal intrinsic clearance data: An examination of in vitro half-life approach and nonspecific binding to microsomes;Obach;Drug Metab Dispos,1999

4. A unified model for predicting human hepatic, metabolic clearance from in vitro intrinsic clearance data in hepatocytes and microsomes;Riley;Drug Metab Dispos,2005

5. Prediction of hepatic clearance and availability by cryopreserved human hepatocytes: An application of serum incubation method;Shibata;Drug Metab Dispos,2002

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