Synthesis of ( R )‐3‐( tert ‐Butoxycarbonylamino)‐4‐(2,4,5‐trifluorophenyl)butanoic Acid, a Key Intermediate, and the Formal Synthesis of Sitagliptin Phosphate-Reference-Cited by-同舟云学术

Synthesis of ( R )‐3‐( tert ‐Butoxycarbonylamino)‐4‐(2,4,5‐trifluorophenyl)butanoic Acid, a Key Intermediate, and the Formal Synthesis of Sitagliptin Phosphate

Published:2020-04-20 Issue:10 Volume:15 Page:1605-1608
ISSN:1861-4728
Container-title:Chemistry – An Asian Journal
language:en
Short-container-title:Chem. Asian J.

Author:

Sreenivasulu Kurella¹,Chaudhari Pramod S.¹,Achanta Srinivas¹,Sud Abhishek¹,Dahanukar Vilas¹,Cobley Christopher J.²,Llewellyn‐Beard Fiona²,Bandichhor Rakeshwar¹^ORCID

Affiliation:

1. Integrated Product DevelopmentInnovation PlazaDr. Reddy's Laboratories Ltd Bachupally, Qutubullapur, R.R. Dist. 500072 Telangana India

2. Integrated Product Development CambridgeDr Reddy's Laboratories Ltd 410 Cambridge Science Park, Milton Road Cambridge CB24 9JU UK

Publisher

Wiley

Subject

General Chemistry,Biochemistry,Organic Chemistry

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/asia.202000092

Reference61 articles.

2. Discovery of JANUVIA™ (Sitagliptin), a Selective Dipeptidyl Peptidase IV Inhibitor for the Treatment of Type2 Diabetes.

3. Unlocking the Potential of Asymmetric Hydrogenation at Merck

4. Dipeptidyl Peptidase IV Inhibitors: The Next Generation of New Promising Therapies for the Management of Type 2 Diabetes

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