Current Concepts in Drug‐Induced Bile Salt Export Pump (BSEP) Interference
Author:
Affiliation:
1. Safety Science Consultant Macclesfield Cheshire United Kingdom
Publisher
Wiley
Subject
Toxicology
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1002/0471140856.tx2307s61
Reference68 articles.
1. Drug-Induced Liver Injury
2. Modeling Drug- and Chemical-Induced Hepatotoxicity with Systems Biology Approaches
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4. Intracellular Drug Concentrations and Transporters: Measurement, Modeling, and Implications for the Liver
5. Vectorial Transport by Double-Transfected Cells Expressing the Human Uptake Transporter SLC21A8 and the Apical Export Pump ABCC2
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2. Quantitative Systems Toxicology and Drug Development: The DILIsym Experience;Methods in Molecular Biology;2022
3. Mechanism‐Based Experimental Models for the Evaluation of BSEP Inhibition and DILI;Transporters and Drug‐Metabolizing Enzymes in Drug Toxicity;2021-07-02
4. Roles of Hepatic Drug Transporters in Drug Disposition and Liver Toxicity;Advances in Experimental Medicine and Biology;2019
5. Can Bile Salt Export Pump Inhibition Testing in Drug Discovery and Development Reduce Liver Injury Risk? An International Transporter Consortium Perspective;Clinical Pharmacology & Therapeutics;2018-10-22
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