Aqueous versus non-aqueous salt delivery strategies to enhance oral bioavailability of a mitogen-activated protein kinase-activated protein kinase (MK-2) inhibitor in rats
Author:
Publisher
Elsevier BV
Subject
Pharmaceutical Science
Reference21 articles.
1. Mitogen-activated protein kinase-activated protein kinase 2 regulates tumor necrosis factor mRNA stability and translation mainly by altering tristetraprolin expression, stability, and binding to adenine/uridine-rich element;Hitti;Mol Cell Biol,2006
2. The involvement of AU-rich element-binding proteins in p38 mitogen-activated protein kinase pathway-mediated mRNA stabilisation;Dean;Cell Signal,2004
3. Tristetraprolin regulates the expression of the human inducible nitric-oxide synthase gene;Fechir;Mol Pharmacol,2005
4. Gene deletion of MK2 inhibits TNF-α and IL-6 and protects against cerulein-induced pancreatitis;Tietz;Am J Physiol Gastrointest Liver Physiol,2006
5. Blockade of the interleukin-21/interleukin-21 receptor pathway ameliorates disease in animal models of rheumatoid arthritis;Young;Arthritis Rheum,2007
Cited by 23 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Evaluating Utilization of Tiny-TIM to Assess the Effect of Food on the Absorptions of Oral Drugs and Its Application on Biopharmaceutical Modeling;Journal of Pharmaceutical Sciences;2024-06
2. Small molecule targeting of the p38/Mk2 stress signaling pathways to improve cancer treatment;BMC Cancer;2023-09-23
3. How to stop disproportionation of a hydrochloride salt of a very weakly basic compound in a non-clinical suspension formulation;International Journal of Pharmaceutics;2021-09
4. Utilizing Tiny-TIM to Assess the Effect of Acid-Reducing Agents on the Absorption of Orally Administered Drugs;Journal of Pharmaceutical Sciences;2021-08
5. High-Throughput Salt Screening of Synthetic Intermediates: Effects of Solvents, Counterions, and Counterion Solubility;Organic Process Research & Development;2020-05-29
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3