Evaluating Utilization of Tiny-TIM to Assess the Effect of Food on the Absorptions of Oral Drugs and Its Application on Biopharmaceutical Modeling-Reference-Cited by-同舟云学术

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Evaluating Utilization of Tiny-TIM to Assess the Effect of Food on the Absorptions of Oral Drugs and Its Application on Biopharmaceutical Modeling

Published:2024-06 Issue:6 Volume:113 Page:1586-1596
ISSN:0022-3549
Container-title:Journal of Pharmaceutical Sciences
language:en
Short-container-title:Journal of Pharmaceutical Sciences

Author:

Liu Jia,Nagapudi Karthik^ORCID,Chiang Po-Chang

Publisher

Elsevier BV

Reference58 articles.

1. FDA: assessing the effects of food on drugs in INDs and NDAs – clinical pharmacology considerations. Docket Number:FDA-2018-D-4368.

2. Biopharmaceutics Modeling and Simulations;Sugano,2012

3. Exploring multi-compartment plug–flow based model approach in biopharmaceutics: impact of stomach setting and the estimation of the fraction absorbed of orally administered basic drugs;Chiang;J Pharm Sci,2020

4. Exploring the use of a kinetic pH calculation to correct the ACAT model with a single stomach compartment setting: impact of stomach setting on food effect prediction for basic compounds;Chiang;J Pharm Sci,2023

5. Upper gastrointestinal (GI) pH in young, healthy men and women;Dressman;Pharm Res,1990

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