Reactivation of Paraoxon-inhibited Acetylcholinesterase by Monoquaternary Pyridinium Oximes withN-Alkylbromide Side Chains-Reference-Cited by-同舟云学术

Reactivation of Paraoxon-inhibited Acetylcholinesterase by Monoquaternary Pyridinium Oximes withN-Alkylbromide Side Chains

Published:2015-12-23 Issue:1 Volume:37 Page:64-68
ISSN:1229-5949
Container-title:Bulletin of the Korean Chemical Society
language:en
Short-container-title:Bull. Korean Chem. Soc.

Author:

Lee Hyun Myung¹²,Shin Jin Soo¹,Han Soo Bong¹²,Jung Yu Kyoung¹²,Kim Meeheyin¹²,Lee Sang-Ho¹,Hur Gyeunghaeng³,Jung Young-Sik¹²

Affiliation:

1. Division of Drug Discovery Research; Korea Research Institute of Chemical Technology; Daejeon 34114 South Korea

2. Department of Medicinal and Pharmaceutical Chemistry; University of Science and Technology; 217 Gajeongro, Yuseong, Daejeon 305-355 Republic of Korea

3. Agency for Defense Development; Daejeon 34188 South Korea

Funder

Defense Basic Research Program

Publisher

Wiley

Subject

General Chemistry

Reference25 articles.

1. Medical Aspects of Chemical and Biological Warfare

2. Progress in the development of enzyme-based nerve agent bioscavengers

3. Pyridinium Oximes as Cholinesterase Reactivators in the Treatment of OP Poisoning

4. Design and synthesis of new bis-pyridinium oxime reactivators for acetylcholinesterase inhibited by organophosphorous nerve agents

Cited by 3 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Discovery of (E)-2-(hydroxyimino)-N-(2 ((4methylpentyl)amino)ethyl)acetamide (KR-27425) as a non-pyridinium oxime reactivator of paraoxon-inhibited acetylcholinesterase;Bioorganic & Medicinal Chemistry Letters;2023-11

2. Comparison of Plasma and Brain Exposure Levels of Bis‐pyridinium Oximes KR‐22839 and KR‐26256 with Asoxime and Obidoxime in Mice;Bulletin of the Korean Chemical Society;2018-12-13

3. Novel tacrine-pyridinium hybrid reactivators of organophosphorus-inhibited acetylcholinesterase: Synthesis, molecular docking, and in vitro reactivation study;Bioorganic & Medicinal Chemistry Letters;2018-12