Novel tacrine-pyridinium hybrid reactivators of organophosphorus-inhibited acetylcholinesterase: Synthesis, molecular docking, and in vitro reactivation study-Reference-Cited by-同舟云学术

Novel tacrine-pyridinium hybrid reactivators of organophosphorus-inhibited acetylcholinesterase: Synthesis, molecular docking, and in vitro reactivation study

Published:2018-12 Issue:23-24 Volume:28 Page:3784-3786
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Kim Jinwoo,Malpani Yashwardhan R.,Lee Jooyun,Shin Jin Soo,Han Soo Bong,Jung Young-Sik

Funder

National Research Foundation of Korea

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference21 articles.

1. Organophosphorus compounds;Lotti,2000

2. Organophosphate poisoning;Marrs;Pharmacol Ther,1993

3. Anticholinesterase agents;Taylor,1996

4. Direct observation and elucidation of the structures of aged and nonaged phosphorylated cholinesterases by phosphorus-31 NMR spectroscopy

5. Structural approach to the aging of phosphylated cholinesterases

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