A new imaging platform ( iScreen ) allows for the concurrent assessment of micronucleus induction and genotoxic mode of action in human A375 cells
Author:
Affiliation:
1. Pfizer Research Development, and Medical Groton Connecticut USA
Publisher
Wiley
Subject
Health, Toxicology and Mutagenesis,Genetics (clinical),Epidemiology
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1002/em.22496
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1. Miniaturized flow cytometry-based CHO-K1 micronucleus assay discriminates aneugenic and clastogenic modes of action
2. Interlaboratory evaluation of a flow cytometric, high content in vitro micronucleus assay
3. Miniaturized flow cytometric in vitro micronucleus assay represents an efficient tool for comprehensively characterizing genotoxicity dose–response relationships
4. Flow cytometric 96-well microplate-based in vitro micronucleus assay with human TK6 cells: Protocol optimization and transferability assessment
5. Genotoxic mode of action predictions from a multiplexed flow cytometric assay and a machine learning approach
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1. Visualization strategies to aid interpretation of high‐dimensional genotoxicity data;Environmental and Molecular Mutagenesis;2024-05-17
2. Comparative analysis of micronucleus induction and DNA damage biomarkers in TK6 and A375 cells using flow cytometry;Environmental and Molecular Mutagenesis;2024-01
3. A novel high-through cell micronucleus detection algorithm based on improved YOLOv5;2023 International Conference on Industrial IoT, Big Data and Supply Chain (IIoTBDSC);2023-09-22
4. Early detection of genotoxic hepatocarcinogens in rats using γH2AX and Ki-67: prediction by machine learning;Toxicological Sciences;2023-08-01
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