Flow cytometric 96-well microplate-based in vitro micronucleus assay with human TK6 cells: Protocol optimization and transferability assessment-Reference-Cited by-同舟云学术

Flow cytometric 96-well microplate-based in vitro micronucleus assay with human TK6 cells: Protocol optimization and transferability assessment

Published:2013-02-27 Issue:3 Volume:54 Page:180-194
ISSN:0893-6692
Container-title:Environmental and Molecular Mutagenesis
language:en
Short-container-title:Environ. Mol. Mutagen.

Author:

Bryce Steven M.¹,Avlasevich Svetlana L.¹,Bemis Jeffrey C.¹,Tate Matthew²,Walmsley Richard M.²,Saad Frédéric³,Van Dijck Kris³,De Boeck Marlies³,Van Goethem Freddy³,Lukamowicz-Rajska Magdalena⁴,Elhajouji Azeddine⁴,Dertinger Stephen D.¹

Affiliation:

1. Litron Laboratories; Rochester; New York

2. Gentronix Ltd. and University of Manchester; Manchester; United Kingdom

3. Janssen Research and Development, A Division of Janssen Pharmaceutical; Genetic and Exploratory Toxicology; Beerse; Belgium

4. Novartis Institutes for Biomedical Research, Preclinical Safety; Genetic Toxicology and Safety Pharmacology; Basel; Switzerland

Publisher

Wiley

Subject

Health, Toxicology and Mutagenesis,Genetics(clinical),Epidemiology

Reference32 articles.

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2. Molecular cytogenetic evaluation of the mechanism of micronucleus formation induced by camptothecin, topotecan, and irinotecan;Attia;Environ Mol Mutagen,2009

3. In vitro micronucleus scoring by flow cytometry: differential staining of micronuclei versus apoptotic and necrotic chromatin enhances assay reliability;Avlasevich;Environ Mol Mutagen,2006

4. Flow cytometric analysis of micronuclei in mammalian cell cultures: past, present and future;Avlasevich;Mutagenesis,2011

5. In vitro micronucleus assay scored by flow cytometry provides a comprehensive evaluation of cytogenetic damage and cytotoxicity;Bryce;Mutat Res,2007

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