Nav1.5 in astrocytes plays a sex-specific role in clinical outcomes in a mouse model of multiple sclerosis

Author:

Pappalardo Laura W.12,Samad Omar A.12,Liu Shujun12,Zwinger Pamela J.12,Black Joel A.12,Waxman Stephen G.12

Affiliation:

1. Department of Neurology and Center for Neuroscience and Regeneration Research; Yale University School of Medicine; New Haven Connecticut, 06510

2. Rehabilitation Research Center; VA Connecticut Healthcare System; West Haven Connecticut, 06516

Funder

National Institutes of General Medical Studies

U.S. Department of Veterans Affairs

Publisher

Wiley

Subject

Cellular and Molecular Neuroscience,Neurology

Reference97 articles.

1. The neuroprotective actions of oestradiol and oestrogen receptors;Arevalo;Nature Reviews Neuroscience,2015

2. Axonal protection using flecainide in experimental autoimmune encephalomyelitis;Bechtold;Annals of Neurology,2004

3. Axonal protection achieved in a model of multiple sclerosis using lamotrigine;Bechtold;Journal of Neurology,2006

4. Axonal protection in experimental autoimmune neuritis by the sodium channel blocking agent flecainide;Bechtold;Brain,2005

5. Glial cells have heart: rH1 Na + channel mRNA and protein in spinal cord astrocytes;Black;Glia,1998

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