Microglia have a more extensive and divergent response to interferon-α compared with astrocytes

Author:

Li Wen1,Viengkhou Barney12,Denyer Gareth2,West Phillip K.12,Campbell Iain L.1,Hofer Markus J.12ORCID

Affiliation:

1. The University of Sydney, School of Molecular Bioscience, the Marie Bashir Institute for Infectious Diseases and Biosecurity, the Charles Perkins Centre, and the Bosch Institute; Sydney Australia

2. The University of Sydney, School of Life and Environmental Sciences; Sydney Australia

Funder

National Health and Medical Research Council

Publisher

Wiley

Subject

Cellular and Molecular Neuroscience,Neurology

Reference72 articles.

1. Transgenic expression of IFN-a in the central nervous system of mice protects against lethal neurotropic viral infection but induces inflammation and neurodegeneration;Akwa;Journal of Immunol,1998

2. Cell biology of astrocyte-synapse interactions;Allen;Neuron,2017

3. Microglia derive from progenitors, originating from the yolk sac, and which proliferate in the brain;Alliot;Brain Research. Developmental Brain Research,1999

4. Human SLFN5 is a transcriptional co-repressor of STAT1-mediated interferon responses and promotes the malignant phenotype in glioblastoma;Arslan;Oncogene,2017

5. Chemokine gene expression in the brain of mice with lymphocytic choriomeningitis;Asensio;Journal of Virology,1997

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