Transcriptomic analysis of IgG4 Fc‐fusion protein degradation in a panel of clonally‐derived CHO cell lines using RNASeq-Reference-Cited by-同舟云学术

Transcriptomic analysis of IgG4 Fc‐fusion protein degradation in a panel of clonally‐derived CHO cell lines using RNASeq

Published:2019-03-21 Issue:6 Volume:116 Page:1556-1562
ISSN:0006-3592
Container-title:Biotechnology and Bioengineering
language:en
Short-container-title:Biotechnology and Bioengineering

Author:

Clarke Colin¹^ORCID,Gallagher Clair²,Kelly Ronan M.³^ORCID,Henry Michael²,Meleady Paula²^ORCID,Frye Christopher C.³,Osborne Matthew D.⁴,Brady Ciaran P³,Barron Niall¹²⁵,Clynes Martin²

Affiliation:

1. National Institute for Bioprocessing Research and TrainingBlackrock, Co. Dublin Ireland

2. National Institute for Cellular BiotechnologyDublin City UniversityGlasnevin Dublin Ireland

3. Bioprocess Research & Development, Bioprocess Research and DevelopmentEli Lilly and Company, LTC‐North Indianapolis

4. Biotech Technical Services/ Manufacturing SciencesEli Lilly S. A. Irish BranchKinsale Cork Ireland

5. UCD School of Chemical and Bioprocess Engineering, UCD Engineering and Materials Science CentreUniversity College DublinBelfield Dublin Ireland

Funder

Science Foundation Ireland

Publisher

Wiley

Subject

Applied Microbiology and Biotechnology,Bioengineering,Biotechnology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/bit.26958

Reference26 articles.

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5. Furin has the proalbumin substrate specificity and serpin inhibitory properties of an in situ hepatic convertase

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