A Unified Mixed-Effects Model for Rare-Variant Association in Sequencing Studies
Author:
Affiliation:
1. Division of Public Health Sciences; Fred Hutchinson Cancer Research Center; Seattle; Washington
Publisher
Wiley
Subject
Genetics (clinical),Epidemiology
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1002/gepi.21717/fullpdf
Reference31 articles.
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2. Hierarchical modeling for estimating relative risks of rare genetic variants: properties of the pseudo-likelihood method;Capanu;Biometrics,2011
3. Enriching the analysis of genome-wide association studies with hierarchical modeling;Chen;Am J Hum Genet,2007
4. Rare variants create synthetic genome-wide associations;Dickson;PLoS Biol,2010
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