Phosphoproteomic analysis reveals compensatory effects in the piriform cortex of VX nerve agent exposed rats

Author:

Nirujogi Raja Sekhar123,Wright James D.4,Manda Srikanth S.125,Zhong Jun6,Na Chan Hyun5,Meyerhoff James7,Benton Bernard4,Jabbour Rabih4,Willis Kristen6,Kim Min-Sik8,Pandey Akhilesh89,Sekowski Jennifer W.4

Affiliation:

1. Institute of Bioinformatics; International Tech Park Bangalore India

2. School of Life Sciences; Centre for Bioinformatics, Pondicherry University; Puducherry India

3. Department of Neuroscience; School of Medicine, Johns Hopkins University; Baltimore MD USA

4. US Army Edgewood Chemical Biological Center, Research and Technology Directorate; Aberdeen Proving Ground; MD USA

5. Department of Neurology; School of Medicine, Johns Hopkins University; Baltimore MD USA

6. Defense Threat Reduction Agency; Fort Belvoir VA USA

7. Oakridge Institute for Science and Engineering; Oakridge TN USA

8. School of Medicine, McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University; Baltimore MD USA

9. Departments of Biological Chemistry; Pathology and Oncology, School of Medicine, Johns Hopkins University; Baltimore MD USA

Funder

Defense Threat Reduction Agency-Joint Science and Technology Office (DTRA-JSTO)

Publisher

Wiley

Subject

Molecular Biology,Biochemistry

Reference64 articles.

1. The U.S. National Academies of Science (NAS) 2004 Health effects of project SHAD chemical agent: VX nerve agent http://www.iom.edu/~/media/Files/Report-%20Files/2007/Long-Term-Health-Effects-of-Participation-in-Project-SHAD-Shipboard-Hazard-and-Defense/VXNERVEAGENT.pdf

2. Primary brian targets of nerve agents: the role of the amygdale in comparison to the hippocampus;Aroniadou-Anderjaska;Neurotoxicology,2009

3. Neurotransmitter changes in guinea-pig brain regions following soman intoxication;Fosbraey;J Neurochem,1990

4. Time-course effects of GA, GB, GD, GF, and VX on the spinal cord cholinesterase and acetylcholinesterase levels in six discrete areas of the rat brain;Benton;Technical Report USA,2001

5. Neuropharmacological mechanisms of nerve agent-induced seizure and neuropathology;McDonough;Neurosci. Biobehav. Rev.,1997

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