Effect of deuteration on the metabolism and clearance of some pharmacologically active compounds-synthesis andin vitrometabolism of deuterated derivatives of dronedadrone-Reference-Cited by-同舟云学术

Effect of deuteration on the metabolism and clearance of some pharmacologically active compounds-synthesis andin vitrometabolism of deuterated derivatives of dronedadrone

Published:2013-07 Issue:9-10 Volume:56 Page:504-512
ISSN:0362-4803
Container-title:Journal of Labelled Compounds and Radiopharmaceuticals
language:en
Short-container-title:J. Label Compd. Radiopharm

Author:

Schofield Joseph¹,Brasseur Denis¹,de Bruin Béatrice¹,Vassal Thierry¹,Klieber Sylvie²,Arabeyre Catherine²,Bourrié Martine²,Sadoun Freddy²,Fabre Gérard²

Affiliation:

1. Isotope Chemistry and Metabolite Synthesis, DSAR-DD; Sanofi R&D; 1 Avenue Pierre Brossolette; 91380; Chilly-Mazarin; France

2. Bioanalysis, Metabolism and In-vitro Methods, DSAR-DD; Sanofi R&D; 371 Rue du Professeur Joseph Blayac; 34184; Montpellier; France

Publisher

Wiley

Subject

Organic Chemistry,Spectroscopy,Drug Discovery,Radiology, Nuclear Medicine and imaging,Biochemistry,Analytical Chemistry

Reference18 articles.

1. Sci-Finder https://scifinder.cas.org/scifinder/

2. Discovery Management Solutions http://www.discoverymanagementsolutions.com/

3. Nature http://www.nature.com/news/2009/090316/full/458269a.html

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