Molecular basis of drug resistance in smoothened receptor: An in silico study of protein resistivity and specificity
Author:
Affiliation:
1. Chemical Engineering and Process Development DivisionCSIR‐National Chemical Laboratory Pune Maharashtra India
2. Academy of Scientific and Innovative Research (AcSIR) Ghaziabad India
Funder
Science and Engineering Research Board
Ministry of Science and Technology
Publisher
Wiley
Subject
Molecular Biology,Biochemistry,Structural Biology
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1002/prot.25830
Reference25 articles.
1. Targeting the Hedgehog Signaling Pathway with Small Molecules
2. Deciphering structural stability and binding mechanisms of potential antagonists with smoothened protein
3. Targeting the Oncoprotein Smoothened by Small Molecules: Focus on Novel Acylguanidine Derivatives as Potent Smoothened Inhibitors
4. Targeting the Sonic Hedgehog Signaling Pathway: Review of Smoothened and GLI Inhibitors
5. Structural basis of Smoothened regulation by its extracellular domains
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