Deciphering structural stability and binding mechanisms of potential antagonists with smoothened protein
Author:
Affiliation:
1. Chemical Engineering and Process Development Division, CSIR-National Chemical Laboratory, Pune, India
2. Academy of Scientific & Innovative Research (AcSIR), CSIR-NCL Campus, Pune, India
Funder
SERB, Ministry of Science and Technology, Government of India
Publisher
Informa UK Limited
Subject
Molecular Biology,General Medicine,Structural Biology
Link
https://www.tandfonline.com/doi/pdf/10.1080/07391102.2017.1372310
Reference60 articles.
1. Vismodegib: A smoothened inhibitor for the treatment of advanced basal cell carcinoma
2. Cell Lines as In Vitro Models for Drug Screening and Toxicity Studies
3. Medicinal Research Reviews
4. Assortative mixing in Protein Contact Networks and protein folding kinetics
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