Facing the challenge of viral mutations in the age of pandemic: Developing highly potent, broad‐spectrum, and safe COVID‐19 vaccines and therapeutics

Author:

Su Shan1,Wang Qian1,Jiang Shibo1ORCID

Affiliation:

1. Key Laboratory of Medical Molecular Virology (MOE/MOH/CAM), School of Basic Medical Sciences Shanghai Institute of Infectious Disease and Biosecurity Fudan University Shanghai China

Publisher

Wiley

Subject

Molecular Medicine,Medicine (miscellaneous)

Reference20 articles.

1. RambautA LomanN PybusO et al.Preliminary Genomic Characterisation of an Emergent SARS‐CoV‐2 Lineage in the UK Defined by a Novel Set of Spike Mutations.2020https://virological.org/t/preliminary-genomic-characterisation-of-an-emergent-sars-cov-2-lineage-in-the-uk-defined-by-a-novel-set-of-spike-mutations/563. Accessed December 21 2020.

2. KupferschmidtK.Mutant Coronavirus in the United Kingdom Sets Off Alarms But Its Importance Remains Unclear.2020.https://www.sciencemag.org/news/2020/12/mutant-coronavirus-united-kingdom-sets-alarms-its-importance-remains-unclear. Accessed December 20 2020.

3. Adaptation of SARS‐CoV‐2 in BALB/c mice for testing vaccine efficacy;Gu H;Science,2020

4. Deep Mutational Scanning of SARS-CoV-2 Receptor Binding Domain Reveals Constraints on Folding and ACE2 Binding

5. Persistence and evolution of SARS‐CoV‐2 in an immunocompromised host;Choi B;N Engl J Med,2020

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