Chiral detection of entecavir stereoisomeric impurities through coordination withR-besivance and ZnIIusing mass spectrometry

Author:

Wang Yali12ORCID,Wang Lu12ORCID,Chen Xiaolei12,Sun Cuirong1,Zhu Yixin3,Kang Yu12,Zeng Su12

Affiliation:

1. Institute of Drug Metabolism and Drug Analysis; College of Pharmaceutical Sciences; Hangzhou 310058 Zhejiang China

2. Zhejiang Province Key Laboratory of Anti-Cancer Drug Research; Zhejiang University; Hangzhou 310058 Zhejiang China

3. Zhejiang Haochuang Biotech Co, Ltd; Hangzhou 311121 Zhejiang China

Funder

National Natural Science Foundation of China

Publisher

Wiley

Subject

Spectroscopy

Reference51 articles.

1. Enantioselective drug-protein interaction between mexiletine and plasma protein;Yu;J Pharm Pharmacol,2012

2. Chiral pharmacology and chiral pharmaceutical analysis;Zeng;Science Press,2009

3. A review of recent advances in mass spectrometric methods for gas phase chiral analysis of pharmaceutical and biological compounds;Wu;J Pharm Biomed Anal,2012

4. Significance and challenges of stereoselectivity assessing methods in drug metabolism;Shen;J Pharm Anal,2016

5. U.S. Food and Drug Administration Compilation Prepared by U.S. Department of Health and Human Services 2011-2014 https://www.fda.gov/Drugs/DevelopmentApprovalProcess/DrugInnovation/default.htm

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