Direct differentiation of stereoisomers of ezetimibe/ambrisentan/atorvastatin and their mechanism study by electrospray ionization quadrupole time-of-flight mass spectrometry
Author:
Affiliation:
1. Institute of Drug Metabolism and Pharmaceutical Analysis; College of Pharmaceutical Sciences; Hangzhou PR China
2. Zhejiang Province Key Laboratory of Anti-Cancer Drug Research; Zhejiang University; Hangzhou PR China
Funder
National Key R&D Program of China
National Natural Science Foundation of China
Publisher
Wiley
Subject
Spectroscopy
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1002/jms.4296/fullpdf
Reference49 articles.
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3. Analysis of stereoisomers of chiral drug by mass spectrometry;Chen;Chirality,2018
4. Quantitative chiral analysis of sugars by electrospray ionization tandem mass spectrometry using modified amino acids as chiral reference compounds;Augusti;Anal Chem,2002
5. Quotient ratio method for quantitative enantiomeric determination by mass spectrometry;Tao;Anal Chem,2002
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1. Improving the Current European Pharmacopoeia Enantio-Selective HPLC Method for the Determination of Enantiomeric Purity in Atorvastatin Calcium Salt Drug Substance;Separations;2024-05-16
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