Bridging mRNA and Polycation Using RNA Oligonucleotide Derivatives Improves the Robustness of Polyplex Micelles for Efficient mRNA Delivery-Reference-Cited by-同舟云学术

Bridging mRNA and Polycation Using RNA Oligonucleotide Derivatives Improves the Robustness of Polyplex Micelles for Efficient mRNA Delivery

Published:2021-12-23 Issue: Volume: Page:2102016
ISSN:2192-2640
Container-title:Advanced Healthcare Materials
language:en
Short-container-title:Adv Healthcare Materials

Author:

Yoshinaga Naoto¹²,Uchida Satoshi¹³⁴^ORCID,Dirisala Anjaneyulu⁴,Naito Mitsuru⁵,Koji Kyoko¹,Osada Kensuke⁶,Cabral Horacio¹,Kataoka Kazunori⁴^ORCID

Affiliation:

1. Department of Bioengineering Graduate School of Engineering The University of Tokyo 7‐3‐1 Hongo Bunkyo‐ku Tokyo 113‐8656 Japan

2. Biomacromolecule Research Team RIKEN Center for Sustainable Resource Science 2‐1 Hirosawa, Wakoshi Saitama 351‐0198 Japan

3. Medical Chemistry Graduate School of Medical Science Kyoto Prefectural University of Medicine 1‐5 Shimogamohangi‐cho Sakyo‐ku Kyoto 606‐0823 Japan

4. Innovation Center of NanoMedicine (iCONM) Kanagawa Institute of Industrial Promotion 3‐25‐14 Tonomachi, Kawasaki‐ku Kawasaki 210‐0821 Japan

5. Center for Disease Biology and Integrative Medicine Graduate School of Medicine The University of Tokyo 7‐3‐1 Hongo Bunkyo‐ku Tokyo 113‐0033 Japan

6. Institute for Quantum Medical Science National Institutes for Quantum Science and Technology (QST) 4‐9‐1 Anagawa, Inage‐ku Chiba‐shi Chiba 263‐8555 Japan

Funder

Ministry of Education, Culture, Sports, Science and Technology

Japan Science and Technology Agency

Japan Agency for Medical Research and Development

Publisher

Wiley

Subject

Pharmaceutical Science,Biomedical Engineering,Biomaterials

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/adhm.202102016

Reference35 articles.

1. In Vivo Messenger RNA Introduction into the Central Nervous System Using Polyplex Nanomicelle

2. Block Copolymer Micelles in Nanomedicine Applications

3. Design concepts of polyplex micelles forin vivotherapeutic delivery of plasmid DNA and messenger RNA

4. Block copolymer micelles for drug delivery: design, characterization and biological significance

5. Systemic delivery of messenger RNA for the treatment of pancreatic cancer using polyplex nanomicelles with a cholesterol moiety

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