Genetic Engineering in Combination with Semi‐Synthesis Leads to a New Route for Gram‐Scale Production of the Immunosuppressive Natural Product Brasilicardin A-Reference-Cited by-同舟云学术

Genetic Engineering in Combination with Semi‐Synthesis Leads to a New Route for Gram‐Scale Production of the Immunosuppressive Natural Product Brasilicardin A

Published:2021-05 Issue:24 Volume:60 Page:13536-13541
ISSN:1433-7851
Container-title:Angewandte Chemie International Edition
language:en
Short-container-title:Angew. Chem. Int. Ed.

Author:

Botas Alma¹,Eitel Michael²,Schwarz Paul N.³,Buchmann Anina⁴,Costales Paula⁵,Núñez Luz Elena⁵,Cortés Jesús⁵^ORCID,Morís Francisco⁵,Krawiec Michał⁶,Wolański Marcin⁶^ORCID,Gust Bertolt⁴^ORCID,Rodriguez Mirna⁷,Fischer Wolf‐Nicolas⁷^ORCID,Jandeleit Bernd⁷^ORCID,Zakrzewska‐Czerwińska Jolanta⁶^ORCID,Wohlleben Wolfgang³,Stegmann Evi³,Koch Pierre²^ORCID,Méndez Carmen¹^ORCID,Gross Harald⁴^ORCID

Affiliation:

1. Departamento de Biología Funcional e Instituto Universitario de Oncología del Principado de Asturias Universidad de Oviedo and Instituto de Investigación Sanitaria de Asturias (ISPA) c/ Julián Clavería s/n. 33006 Oviedo Spain

2. Department of Pharmaceutical Chemistry Institute of Pharmaceutical Sciences University of Tübingen Auf der Morgenstelle 8 72076 Tübingen Germany

3. Department of Microbiology and Biotechnology Interfaculty Institute of Microbiology and Infection Medicine University of Tübingen Auf der Morgenstelle 28 72076 Tübingen Germany

4. Department of Pharmaceutical Biology Institute of Pharmaceutical Sciences University of Tübingen Auf der Morgenstelle 8 72076 Tübingen Germany

5. EntreChem S.L. Vivero Ciencias de la Salud c/ Colegio Santo Domingo de Guzmán, s/n 33011 Oviedo Spain

6. Department of Molecular Microbiology Faculty of Biotechnology University of Wrocław ul. F. Joliot-Curie 14A 50-383 Wrocław Poland

7. Quadriga BioSciences, Inc. 339 S. San Antonio Road, Suite 2A Los Altos CA 94022 USA

Funder

Bundesministerium für Bildung und Forschung

Ministerstwo Nauki i Szkolnictwa Wyższego

Publisher

Wiley

Subject

General Chemistry,Catalysis

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/anie.202015852

Reference37 articles.

1. Developing New Immunosuppression for the Next Generation of Transplant Recipients: The Path Forward

3. Minimizing Immunosuppression, an Alternative Approach to Reducing Side Effects: Objectives and Interim Result

4. Immunosuppressive therapies after heart transplantation — The balance between under- and over-immunosuppression

5. J. Andrade-Sierra P. A. Vazquez-Galvan H. Hernandez-Reyes L. A. Mercado-Jáuregui J. S. Chávez-Iñiguez E. González-Espinoza B. Gómez-Navarro J. I. Cerrillos-Gutiérrez Current Status and Future Challenges(Ed.: G. Tsoulfas) IntechOpen https://doi.org/10.5772/intechopen.77292 2018.

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