Translocation of an antibody transgene requires AID and occurs by interchromosomal switching to all switch regions except the mu switch region
Author:
Publisher
Wiley
Subject
Immunology,Immunology and Allergy
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1002/eji.201041077/fullpdf
Reference34 articles.
1. Mechanism and regulation of class switch recombination;Stavnezer;Annu. Rev. Immunol.,2008
2. Interallelic class switch recombination contributes significantly to class switching in mouse B cells;Reynaud;J. Immunol.,2005
3. Interallelic class switch recombination can reverse allelic exclusion and allow trans-complementation of an IgH locus switching defect;Dougier;Eur. J. Immunol.,2006
4. Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme;Muramatsu;Cell,2000
5. Activation-induced cytidine deaminase deaminates deoxycytidine on single-stranded DNA but requires the action of RNase;Bransteitter;Proc. Natl. Acad. Sci. USA,2003
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1. Rabbits transgenic for human IgG genes recapitulating rabbit B-cell biology to generate human antibodies of high specificity and affinity;mAbs;2020-01-01
2. Alternative end-joining pathway(s): Bricolage at DNA breaks;DNA Repair;2014-05
3. Human antibody expression in transgenic rats: Comparison of chimeric IgH loci with human VH, D and JH but bearing different rat C-gene regions;Journal of Immunological Methods;2013-12
4. Transgenes of the Mouse Immunoglobulin Heavy Chain Locus, Lacking Distal Elements in the 3′ Regulatory Region, Are Impaired for Class Switch Recombination;PLoS ONE;2013-02-08
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