Human antibody expression in transgenic rats: Comparison of chimeric IgH loci with human VH, D and JH but bearing different rat C-gene regions

Author:

Ma Biao,Osborn Michael J.,Avis Suzanne,Ouisse Laure-Hélène,Ménoret Séverine,Anegon Ignacio,Buelow Roland,Brüggemann Marianne

Funder

OMT

Biogenouest and Région Pays de la Loire, France

Publisher

Elsevier BV

Subject

Immunology,Immunology and Allergy

Reference42 articles.

1. The pre-B cell receptor; selecting for or against autoreactivity;Almqvist;Scand. J. Immunol.,2012

2. Three classes and four (sub)classes of rat immunoglobulins: IgM, IgA, IgE and IgG1, IgG2a, IgG2b, IgG2c;Bazin;Eur. J. Immunol.,1974

3. Immunoglobulin heavy chain locus of the rat: striking homology to mouse antibody genes;Bruggemann;Proc. Natl. Acad. Sci. U. S. A.,1986

4. A matched set of rat/mouse chimeric antibodies. Identification and biological properties of rat H chain constant regions mu, gamma 1, gamma 2a, gamma 2b, gamma 2c, epsilon, and alpha;Bruggemann;J. Immunol.,1989

5. Human antibody production in transgenic mice: expression from 100kb of the human IgH locus;Bruggemann;Eur. J. Immunol.,1991

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