Rabbits transgenic for human IgG genes recapitulating rabbit B-cell biology to generate human antibodies of high specificity and affinity-Reference-Cited by-同舟云学术

Rabbits transgenic for human IgG genes recapitulating rabbit B-cell biology to generate human antibodies of high specificity and affinity

Published:2020-01-01 Issue:1 Volume:12 Page:
ISSN:1942-0862
Container-title:mAbs
language:en
Short-container-title:mAbs

Author:

Ros Francesca¹,Offner Sonja¹,Klostermann Stefan²,Thorey Irmgard¹,Niersbach Helmut³,Breuer Sebastian¹,Zarnt Grit¹,Lorenz Stefan¹,Puels Juergen⁴,Siewe Basile⁵,Schueler Nicole¹,Dragicevic Tajana¹,Ostler Dominique¹,Hansen-Wester Imke⁶,Lifke Valeria⁷,Kaluza Brigitte¹,Kaluza Klaus¹,van Schooten Wim⁸,Buelow Roland⁸,Tissot Alain C¹,Platzer Josef¹

Affiliation:

1. Roche Pharmaceutical Research and Early Development, Large Molecule Research, Roche Innovation Center Munich, Penzberg, Germany

2. Roche Pharmaceutical Research and Early Development, Informatics, Roche Innovation Center Munich, Penzberg, Germany

3. Roche Pharmaceutical Research and Early Development, Pharmaceutical Sciences, Roche Innovation Center Munich, Penzberg, Germany

4. TÜV SÜD Product Service GmbH, Munich, Germany

5. THE JACKSON LABORATORY JMCRS, Sacramento, CA, USA

6. Supplier Quality Management, Global External Quality Roche Diagnostics GmbH, Penzberg, Germany

7. Personalized Healthcare Solution, Immunoassay Development and System Integration, Roche Diagnostics GmbH, Penzberg, Germany

8. Teneobio, Inc., Newark, CA, USA

Funder

Roche Pharmaceutical Research and Early Development, Large Molecule Research, Roche Innovation Center Munich, Penzberg, Germany

Therapeutic Human Polyclonals, Inc

Publisher

Informa UK Limited

Subject

Immunology,Immunology and Allergy

Link

https://www.tandfonline.com/doi/pdf/10.1080/19420862.2020.1846900

Reference50 articles.

1. Antibodies to watch in 2018

2. Strategies for Generating Diverse Antibody Repertoires Using Transgenic Animals Expressing Human Antibodies

3. Rabbit Monoclonal Antibodies

4. Rabbit Hybridoma

5. Restricted VH Gene Usage and Generation of Antibody Diversity in Rabbit

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