Affiliation:
1. Department of Chemistry Faculty of Science Muğla Sıtkı Koçman University 48000 Muğla Turkey
2. Department of Chemistry and Chemical Processing Technologies Muğla Vocational School Muğla Sıtkı Koçman University 48000 Muğla Turkey
3. Department of Medical Services and Techniques Köyceğiz Vocational School of Health Services Muğla Sıtkı Koçman University 48000 Köyceğiz/Muğla Turkey
4. Food Quality Control and Analysis Program Ula Ali Kocman Vocational School Mugla Sitki Kocman University 48147 Mugla Turkey
Abstract
AbstractSunflower honey (SH) is bright yellow, fragrant, pollen‐flavoured, slightly herbaceous and has a unique taste. The present research aims to examine the enzyme inhibitory, antioxidant, anti‐inflammatory, antimicrobial and anti‐quorum sensing activities and phenolic compositions of 30 sunflower honeys (SHs) produced from several regions of Turkey with chemometric study. SAH from Samsun exhibited the best antioxidant activity in β‐carotene linoleic acid (IC50: 7.33±0.17 mg/mL) and CUPRAC (A0.50: 4.94±0.13 mg/mL) assays, anti‐urease activity (60.63±0.87 %) and anti‐inflammatory activity against COX‐1 (73.94±1.08 %) and COX‐2 (44.96±0.85 %). SHs exhibited mild antimicrobial activity against the test microorganisms while they showed high quorum sensing inhibition zones measured in the range of 42–52 mm against the CV026 strain. The phenolic composition was determined by high performance liquid chromatography with diode array detection (HPLC‐DAD) system and levulinic, gallic, p‐hydroxybenzoic, vanillic and p‐coumaric acids were identified in all studied SHs. The classification of SHs was performed the using PCA and HCA. This study revealed that phenolic compounds and biological properties are effective in classification of SHs according to their geographical origin. The results suggest that studied SHs could be valued as potential agents with versatile bioactivities in oxidative stress‐related disease, microbial infections, inflammation, melanoma, and peptic ulcer.
Subject
Molecular Biology,Molecular Medicine,General Chemistry,Biochemistry,General Medicine,Bioengineering
Cited by
2 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献