Undescribed Triterpenes from the Leaves of Syzygium myrsinifolium with Their α‐Glucosidase and α‐Amylase Inhibition Activity

Author:

Trang Do Thi1,Tai Bui Huu12,Hoang Nguyen Huy1,Cuc Nguyen Thi1,Bang Ngo Anh1,Dung Duong Thi1,Yen Duong Thi Hai1,Huong Phan Thi Thanh1,Dung Nguyen Viet1,Hang Dan Thi Thuy1,Yen Pham Hai1,Kiem Phan Van12ORCID

Affiliation:

1. Institute of Marine Biochemistry, VAST 18 Hoang Quoc Viet, Cau Giay Hanoi 10072 Vietnam

2. Graduate University of Science and Technology, VAST 18 Hoang Quoc Viet, Cau Giay Hanoi 10072 Vietnam

Abstract

AbstractTwo undescribed triterpenes, syzyfolium A (1) and syzyfolium B (2), together with twelve known compounds, terminolic acid (3), actinidic acid (4), piscidinol A (5), threo‐dihydroxydehydrodiconiferyl alcohol (6), lariciresinol‐4‐Oβ‐D‐glucoside (7), icariol A2 (8), 14β,15β‐dihydroxyklaineanone (9), garcimangosone D (10), (+)‐catechin (11), myricetin‐3‐Oα‐L‐rhamnopyranoside (12), quercitrin (13), and 3, 4, 5‐trimethoxyphenyl‐(6′‐O‐galloyl)‐Oβ‐D‐glucopyranoside (14) were isolated from the leaves of Syzygium myrsinifolium. Their chemical structures were determined by IR, HR‐ESI‐MS, 1D and 2D NMR spectra. Compounds 3 and 4 inhibited significantly α‐glucosidase with IC50 values of 23.99 and 36.84, respectively, and compounds 1 and 2 inhibited significantly α‐amylase with IC50 values of 35.48 and 43.65 μM, respectively.

Funder

Vietnam Academy of Science and Technology

Publisher

Wiley

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