Continuous‐Flow Hydrogenation and Reductive Deuteration of Nitriles: a Simple Access to α,α‐Dideutero Amines-Reference-Cited by-同舟云学术

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Continuous‐Flow Hydrogenation and Reductive Deuteration of Nitriles: a Simple Access to α,α‐Dideutero Amines

Published:2019-10 Issue:10 Volume:84 Page:1508-1511
ISSN:2192-6506
Container-title:ChemPlusChem
language:en
Short-container-title:ChemPlusChem

Author:

Mészáros Rebeka¹,Peng Bai‐Jing¹²,Ötvös Sándor B.¹³⁴^ORCID,Yang Shyh‐Chyun²⁵⁶,Fülöp Ferenc¹³^ORCID

Affiliation:

1. Institute of Pharmaceutical ChemistryUniversity of Szeged Eötvös u. 6 6720 Szeged Hungary

2. School of Pharmacy, College of PharmacyKaohsiung Medical University Kaohsiung 807 Taiwan

3. MTA-SZTE Stereochemistry Research GroupHungarian Academy of Sciences Eötvös u. 6 6720 Szeged Hungary

4. Institute of ChemistryUniversity of GrazNAWI Graz Heinrichstrasse 28 8010 Graz Austria

5. Department of Fragrance and Cosmetic ScienceCollege of PharmacyKaohsiung Medical University Kaohsiung 807 Taiwan

6. Department of Medical ResearchKaohsiung Medical University HospitalKaohsiung Medical University Kaohsiung 807 Taiwan

Funder

Ministry of Education and Human Resources Development

Publisher

Wiley

Subject

General Chemistry

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/cplu.201900526

Reference80 articles.

1.

2. Synthesis and biological evaluation of BMS-986120 and its deuterated derivatives as PAR4 antagonists

3. Design, synthesis and biological evaluation of deuterated Vismodegib for improving pharmacokinetic properties

4.

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1. Continuous-flow hydrogenation of cinnamaldehyde over catalysts derived from modified CoAl4 layered double hydroxides incorporating Mn, Ni, Cu and Zn ions;Applied Catalysis A: General;2024-06

2. Continuous Hydrogenation of Nitriles to Primary Amines with High Selectivity in Flow by Using Raney Cobalt;ChemistrySelect;2024-04-15

3. Synthesis of Deuterated Compounds by Flow Chemistry;ChemPlusChem;2024-04-04

4. Organophotocatalytic α-deuteration of unprotected primary amines via H/D exchange with D₂O;Chemical Communications;2024

5. Research Progress of Continuous Flow Selective Hydrogenation Technology;Chinese Journal of Organic Chemistry;2024

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