A physiologically based pharmacokinetic model to predict the pharmacokinetics of highly protein-bound drugs and the impact of errors in plasma protein binding-Reference-Cited by-同舟云学术

A physiologically based pharmacokinetic model to predict the pharmacokinetics of highly protein-bound drugs and the impact of errors in plasma protein binding

Published:2016-04 Issue:3 Volume:37 Page:123-141
ISSN:0142-2782
Container-title:Biopharmaceutics & Drug Disposition
language:en
Short-container-title:Biopharm. Drug Dispos.

Author:

Ye Min¹,Nagar Swati¹,Korzekwa Ken¹

Affiliation:

1. Department of Pharmaceutical Science; Temple University School of Pharmacy; Philadelphia PA 19140 USA

Funder

National Institutes of Health

Publisher

Wiley

Subject

Pharmacology (medical),Pharmaceutical Science,Pharmacology,General Medicine

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/bdd.1996/fullpdf

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3. Kinetic determinants of hepatic clearance: plasma protein binding and hepatic uptake;Baker;Xenobiotica,2007

4. Impact of pH on plasma protein binding in equilibrium dialysis;Kochansky;Mol Pharm,2008

5. A priori prediction of tissue:plasma partition coefficients of drugs to facilitate the use of physiologically-based pharmacokinetic models in drug discovery;Poulin;J Pharm Sci,2000

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