Reversible dissociation and unfolding of the dimeric protein thymidylate synthase
Author:
Publisher
Wiley
Subject
Molecular Biology,Biochemistry
Reference17 articles.
1. Secondary α-hydrogen isotope effects on the interaction of 5-fluoro-2′-deoxyuridylate and 5,10-methylenetetrahydrofolate with thymidylate synthetase;Bruice;Biochemistry,1982
2. Saturated site-directed mutagenesis of thymidylate synthase;Climie;J. Biol. Chem.,1990
3. Chemical synthesis of the thymidylate synthase gene;Climie;Proc. Natl. Acad. Sci. USA,1990
4. Reversible inactivation and reactivation of thymidylate synthetase;Freidkin;Adv. Enzyme Regul.,1972
5. Atomic structure of thymidylate synthase: Target for rational drug design;Hardy;Science,1987
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