Brd4‐Brd2 isoform switching coordinates pluripotent exit and Smad2‐dependent lineage specification-Reference-Cited by-同舟云学术

Brd4‐Brd2 isoform switching coordinates pluripotent exit and Smad2‐dependent lineage specification

Published:2017-06-06 Issue:7 Volume:18 Page:1108-1122
ISSN:1469-221X
Container-title:EMBO reports
language:en
Short-container-title:EMBO Rep

Author:

Fernandez‐Alonso Rosalia¹,Davidson Lindsay²,Hukelmann Jens³,Zengerle Michael⁴,Prescott Alan R³,Lamond Angus³^ORCID,Ciulli Alessio⁴,Sapkota Gopal P¹,Findlay Greg M¹^ORCID

Affiliation:

1. The MRC Protein Phosphorylation and Ubiquitylation Unit School of Life Sciences The University of Dundee Dundee UK

2. Pluripotent Stem Cell Facility School of Life Sciences The University of Dundee Dundee UK

3. Centre for Gene Regulation and Expression School of Life Sciences The University of Dundee Dundee UK

4. Biological Chemistry and Drug Discovery School of Life Sciences The University of Dundee Dundee UK

Funder

Tenovus

Medical Research Council

H2020 European Research Council

Publisher

EMBO

Subject

Genetics,Molecular Biology,Biochemistry

Link

https://onlinelibrary.wiley.com/doi/pdf/10.15252/embr.201643534

Reference48 articles.

1. iPS cells: a game changer for future medicine

2. Differentiation of Embryonic Stem Cells to Clinically Relevant Populations: Lessons from Embryonic Development

3. Mice exclusively expressing the short isoform of Smad2 develop normally and are viable and fertile

4. Differential requirements for Smad4 in TGFβ-dependent patterning of the early mouse embryo

5. TGFβ signalling in context

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