Phytochemistry, Toxicology, and Pharmacological Properties of Origanum elongatum

Author:

Abdelaali Balahbib1ORCID,El Menyiy Naoual2ORCID,El Omari Nasreddine3ORCID,Benali Taoufiq4,Guaouguaou Fatima-Ezzahrae5,Salhi Najoua6,Naceiri Mrabti Hanae6ORCID,Bouyahya Abdelhakim7ORCID

Affiliation:

1. Laboratory of Biodiversity, Ecology and Genome, Mohammed V University in Rabat, Rabat, Morocco

2. Laboratory of Physiology, Pharmacology and Environmental Health, University Sidi Mohamed Ben Abdellah, Fez, Morocco

3. Laboratory of Histology, Embryology, and Cytogenetic, Mohammed V University in Rabat, Rabat, Morocco

4. Environment and Health Team, Polydisciplinary Faculty of Safi, Cadi Ayyad University, Marrakech, Morocco

5. Mohammed V University in Rabat, LPCMIO, Materials Science Center (MSC), Ecole Normale Supérieure, Rabat, Morocco

6. Laboratory of Pharmacology and Toxicology, Faculty of Medicine and Pharmacy, Mohammed V University in Rabat, BP 6203, Rabat, Morocco

7. Laboratory of Human Pathologies Biology, Department of Biology, Mohammed V University in Rabat, Rabat, Morocco

Abstract

Origanum elongatum L. is an endemic aromatic and medicinal plant. This work reports previous studies on O. elongatum concerning its taxonomy, botanical description, geographical distribution, bioactive compounds, toxicology, and biological effects. Chemical analyses showed that O. elongatum contains different chemical compounds, in particular volatile compounds. Pharmacological investigations showed that volatile compounds and extracts from O. elongatum exhibit different pharmacological properties, such as antibacterial, antifungal, antiviral, antioxidant, vasodilator, corrosion inhibitor, and hepatoprotective effects. Moreover, toxicological reports revealed the safety of this species. The pharmacological effects of O. elongatum could be correlated with the main compounds, which exhibit different pharmacological properties with numerous mechanism insights.

Publisher

Hindawi Limited

Subject

Complementary and alternative medicine

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