Synthesis, Characterization, and Antioxidant Activities of Genistein, Biochanin A, and Their Analogues

Abstract

A series of naturally occurring genistein(3)and biochanin A(4)compounds and their analogues were synthesized from phloroglucinol. The structures of all the synthesized compounds were established by the combined use ofHNMR1,CNMR13, IR spectral data, and mass spectrometry; their antioxidant activities were investigated. Most of the synthesized compounds show moderate-to-high activity; only two compounds exhibit no significant activity.