A Review on Synthesis and Biological Potential of Dihydropyridines-Reference-Cited by-同舟云学术

A Review on Synthesis and Biological Potential of Dihydropyridines

Published:2024-01 Issue:1 Volume:21 Page:15-33
ISSN:1570-1808
Container-title:Letters in Drug Design & Discovery
language:en
Short-container-title:LDDD

Author:

Pathak Shilpi¹,Jain Supriya²,Pratap Abhishek¹

Affiliation:

1. Institute of Pharmaceutical Research, GLA University, Mathura, Uttar Pradesh, 281406, India

2. Institute of Business Management, GLA University, Mathura, Uttar Pradesh, 281406, India

Abstract

Abstract: Dihydropyridine is an outstanding heterocyclic compound with a wide range of pharmacological potential, including antimicrobial, antioxidant, antitubercular, antiarrhythmic, insecticidal, antihypertensive, vasodilator, anti-inflammatory, antibacterial, antidiabetic and superlative moiety in drug discovery. It is also a versatile pharmacophore, a privileged scaffold, and a distinguished heterocyclic compound. Excellent outcomes have already been shown with novel targets and various modes of action for the dihydropyridines hybrids. This review focused on the mode of action, synthesis, and biological activities. As a result, numerous dihydropyridine candidates are undergoing clinical studies to treat various disorders. This article highlights how novel techniques were used to create dihydropyridines, which may be helpful to researchers in the future.

Publisher

Bentham Science Publishers Ltd.

Subject

Drug Discovery,Pharmaceutical Science,Molecular Medicine

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