Low pHoboosts burst firing and catecholamine release by blocking TASK-1 and BK channels while preserving Cav1 channels in mouse chromaffin cells
Author:
Affiliation:
1. Department of Drug Science, Laboratory of Cellular and Molecular Neuroscience, NIS Centre; CNISM Unit; Torino Italy
2. Present address: Institute of Science and Technology Austria, Am Campus 1; Klosterneuburg Austria
Funder
Ministero dell’Istruzione, dell’Università e della Ricerca
University of Torino
Fondazione Telethon
Publisher
Wiley
Subject
Physiology
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1113/JP273735/fullpdf
Reference64 articles.
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3. Ligand-gating by Ca2+ is rate limiting for physiological operation of BK(Ca) channels;Berkefeld;J Neurosci,2013
4. Intravesicular factors controlling exocytosis in chromaffin cells;Borges;Cell Mol Neurobiol,2010
5. Protons block BK channels by competitive inhibition with K+ and contribute to the limits of unitary currents at high voltages;Brelidze;J Gen Physiol,2004
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