Potential impact of cytochrome P450 3A5 in human liver on drug interactions with triazoles

Author:

Yamazaki Hiroshi,Nakamoto Minako,Shimizu Makiko,Murayama Norie,Niwa Toshiro

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

Reference25 articles.

1. Cytochrome P450 and chemical toxicology;Guengerich;Chem Res Toxicol,2008

2. Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: studies with liver microsomes of 30 Japanese and 30 Caucasians;Shimada;J Pharmacol Exp Ther,1994

3. Cytochrome P4503A (CYP3A) metabolism: prediction of in vivo activity in humans;Wilkinson;J Pharmacokin Biopharm,1996

4. Sequence diversity in CYP3A promoters and characterization of the genetic basis of polymorphic CYP3A5 expression;Kuehl;Nat Genet,2001

5. Ethnic differences between Japanese and Caucasians in the expression levels of mRNAs for CYP3A4, CYP3A5 and CYP3A7: lack of co-regulation of the expression of CYP3A in Japanese livers;Yamaori;Xenobiotica,2005

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