2D- and 3D-Quantitative Structure-Activity Relationship Studies for a Series of Phenazine N,N’-Dioxide as Antitumour Agents

Author:

Cunha Jonathan Da,Lavaggi María Laura,Abasolo María Inés,Cerecetto Hugo,González Mercedes

Publisher

Wiley

Subject

Molecular Medicine,Biochemistry,Drug Discovery,Pharmacology,Organic Chemistry

Reference28 articles.

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2. Hypoxia enhances metastatic efficiency by up-regulating Mdm2 in KHT cells and increasing resistance to apoptosis;Zhang;Cancer Res,2004

3. Role of hypoxia in the hallmarks of human cancer;Ruan;Cell Biochem,2009

4. The role of hypoxia-activated drugs in cancer therapy;Denny;Oncology,2000

5. Phenazine 5,10-dioxide derivatives as hypoxic selective cytotoxins;Cerecetto;J Med Chem,2005

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