Phenazine 5,10-Dioxide Derivatives as Hypoxic Selective Cytotoxins-Reference-Cited by-同舟云学术

Phenazine 5,10-Dioxide Derivatives as Hypoxic Selective Cytotoxins

Published:2004-12-17 Issue:1 Volume:48 Page:21-23
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Cerecetto Hugo¹,González Mercedes¹,Lavaggi Ma Laura¹,Azqueta Amaia¹,López de Cerain Adela¹,Monge Antonio¹

Affiliation:

1. Departamento de Química Orgánica, Facultad de Química-Facultad de Ciencias, Universidad de la República, Uruguay, and Centro de Investigaciones en Farmacobiología Aplicada, Universidad de Navarra, Pamplona, España

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm0492150

Reference10 articles.

1. Bioreducible mustards: a paradigm for hypoxia-selective prodrugs of diffusible cytotoxins (HPDCs)

2. Synthesis and antidepressant activity of 5-phenyl-2-(2-propynylamino)-2-oxazolin-4-one and derivatives

3. SR 4233 (Tirapazamine): a new anticancer drug exploiting hypoxia in solid tumours

4. Rationale for the use of aliphatic N-oxides of cytotoxic anthraquinones as prodrug DNA binding agents: a new class of bioreductive agent

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