Electroreduction of Derivatives of N,N'-Dioxides of Phenazine and Quinoxaline in Nonaqueous Media and in the Presence of Proton Donors of Medium Strength

Author:

Mikhal’chenko L. V.,Nasybullina D. V.,Leonova M. Yu.,Syroeshkin M. A.,Gul’tyai V. P.

Publisher

Pleiades Publishing Ltd

Subject

Electrochemistry

Reference26 articles.

1. Da Cunha, J., Lavaggi, M.L., Abasolo, M.I., Cerecetto, H., and Gonzalez M., 2D- and 3D-quantitative structure-activity relationship studies for a series of phenazine N,N'-dioxide as antitumour agents, Chem. Biol. Drug Des., 2011, vol. 78, p. 960.

2. Pachon, O. G., Azqueta, A., Lavaggi, M.L., Lopez de Cerain, A., Creppy, E., Collins, A., Cerecetto H., Gonzalez, M., Centelles, J.J., and Cascante, M., Antitumoral effect of phenazine N5,N10-dioxide derivatives on caco-2 cells, Chem. Res. Toxicol., 2008, vol. 21, p. 1578.

3. Gonda, M., Nieves, M., Nunes, E., Lopez de Cerain, A., Monge, A., Lavaggi, M. L., Gonzalez, M., and Cerecetto, H., Phenazine N,N0-dioxide scaffold as selective hypoxic cytotoxin pharmacophore. Structural modifications looking for further DNA topoisomerase II-inhibition activity, Med. Chem. Commun., 2013, no. 4, p. 595.

4. Lavaggi, M.L., Cabrera, M., Pintos, C., Arredondo, C., Pachon, G., Rodrıguez, J., Raymondo, S., Pacheco, J.P., Cascante, M., Olea-Azar, C., Lopez de Cerain, A., Monge, A., Cerecetto, H., and Gonzalez, M., Novel phenazine 5,10-dioxides release •OH in simulated hypoxia and induce reduction of tumour volume in vivo, ISRN Pharmacol., 2011, Article ID 314209. https://doi.org/10.5402/2011/314209

5. Chowdhury, G., Sarkar, U., Pullen, S., Wilson, W.R, Rajapakse, A., Fuchs-Knotts, T., and Gates, K.S., DNA strand cleavage by the phenazine di-N-oxide natural product myxin under both aerobic and anaerobic conditions, Chem. Res. Toxicol., 2012, vol. 25, p. 197. https://doi.org/10.1021/tx2004213

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