Antigen‐specific in vitro expansion of factor VIII‐specific regulatory T cells induces tolerance in hemophilia A mice
Author:
Affiliation:
1. Center for Immunity and Immunotherapies Seattle Children's Research Institute Seattle Washington
2. Department of Pediatrics University of Washington Seattle Washington
Funder
National Heart, Lung, and Blood Institute
Publisher
Wiley
Subject
Hematology
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1111/jth.14659
Reference64 articles.
1. How we choose factor VIII to treat hemophilia
2. Distinct characteristics of antibody responses against factor VIII in healthy individuals and in different cohorts of hemophilia A patients
3. Late immune tolerance induction in haemophilia A patients
4. Immune tolerance induction in haemophilia A patients with inhibitors by treatment with recombinant factor VIII: a retrospective non-interventional study
5. A murine model for induction of long-term immunologic tolerance to factor VIII does not require persistent detectable levels of plasma factor VIII and involves contributions from Foxp3+ T regulatory cells
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