Harnessing CD8 + T‐cell exhaustion to treat type 1 diabetes
Author:
Affiliation:
1. St Vincent’s Institute Fitzroy VIC3065Australia
2. Department of Medicine St Vincent’s HospitalThe University of Melbourne Fitzroy VIC3065Australia
Funder
National Health and Medical Research Council
Publisher
Wiley
Subject
Cell Biology,Immunology,Immunology and Allergy
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1111/imcb.12444
Reference84 articles.
1. Autoreactive T cells in type 1 diabetes
2. Pathogenic Mechanisms in Type 1 Diabetes: The Islet is Both Target and Driver of Disease
3. Clonal Deletion Prunes but Does Not Eliminate Self-Specific αβ CD8+ T Lymphocytes
4. Islet-reactive CD8 + T cell frequencies in the pancreas, but not in blood, distinguish type 1 diabetic patients from healthy donors
5. Presumption of innocence for beta cells: why are they vulnerable autoimmune targets in type 1 diabetes?
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1. Interconnected lineage trajectories link conventional and natural killer (NK)-like exhausted CD8+ T cells beneficial in type 1 diabetes;Communications Biology;2024-06-27
2. TRAJ23 Gene Targeting as a Therapeutic Strategy for Type 1 Diabetes: Implications from NOD Mouse Model Studies;2024-06-14
3. Autoimmune CD8+ T cells in type 1 diabetes: from single-cell RNA sequencing to T-cell receptor redirection;Frontiers in Endocrinology;2024-05-10
4. Update on the ZNT8 epitope and its role in the pathogenesis of type 1 diabetes;Minerva Endocrinology;2023-12
5. A Concerted Vision to Advance the Knowledge of Diabetes Mellitus Related to Immune Checkpoint Inhibitors;International Journal of Molecular Sciences;2023-04-21
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